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Tivic VNS Optimization Study

Tivic has already confirmed the effectiveness of its non-invasive cervical vagus nerve stimulation (ncVNS) platform. Data show Tivic’s platform induces responses in the autonomic, cardiac, and central nervous systems. A current trial, which is being conducted by The Feinstein Institute of Bioelectronic Medicine is now underway to identify device parameters that optimally influence autonomic nervous system (ANS) function, including the frequency and the duration of potential treatments. Tivic Health plans to use these results to prioritize clinical indications it will carry forward into further testing and commercial development.
The clinical trial showing the effectiveness of Tivic’s ClearUP® product technology was published in the peer-reviewed publication International Forum of Allergy & Rhinology and is titled

Microcurrent technology for rapid relief of sinus pain: a randomized, placebo‐controlled, double‐blinded clinical trial.

Maul, X. A., Borchard, N. A., Hwang, P. H., & Nayak, J. V. (2019, April). In International forum of allergy & rhinology (Vol. 9, No. 4, pp. 352-356).

Learn more about Tivic’s Prospective trial examining safety and efficacy of microcurrent stimulation for the treatment of sinus pain and congestion, which found that self-administered periorbital microcurrent treatment given at home was efficacious in significantly reducing moderate sinus pain for up to 6 hours and significantly reducing moderate pain and congestion over 4 weeks of daily use. Microcurrent therapy was found to be safe with only minor side effects that resolved without intervention.

The study was published in the peer-reviewed journal Bioelectronic Medicine. Goldsobel, A. B., Prabhakar, N., & Gurfein, B. T. (2019). Bioelectronic medicine, 5(1), 1-9.

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